--- product_id: 16666788 title: "Central Life Sciences 6-Pack Comfort Zone Refill with Dog Appeasing Pheromone, 288ml" brand: "central life sciences" price: "€ 164.84" currency: EUR in_stock: false reviews_count: 8 category: "Pet Supplies" url: https://www.desertcart.pt/products/16666788-central-life-sciences-6-pack-comfort-zone-refill-with-dog store_origin: PT region: Portugal --- # Central Life Sciences 6-Pack Comfort Zone Refill with Dog Appeasing Pheromone, 288ml **Brand:** central life sciences **Price:** € 164.84 **Availability:** ❌ Out of Stock ## Quick Answers - **What is this?** Central Life Sciences 6-Pack Comfort Zone Refill with Dog Appeasing Pheromone, 288ml by central life sciences - **How much does it cost?** € 164.84 with free shipping - **Is it available?** Currently out of stock - **Where can I buy it?** [www.desertcart.pt](https://www.desertcart.pt/products/16666788-central-life-sciences-6-pack-comfort-zone-refill-with-dog) ## Best For - central life sciences enthusiasts ## Why This Product - Trusted central life sciences brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Description Reduces or completely stops stress-related behavior including: barking, whimpering and whining, chewing, urination and defecation. Also reduces or eliminates separation anxiety. ## Features - 6 pack of D.A.P refills mimics a natural reassuring pheromone produced by female dogs when nursing - Calms dogs during thunderstorms and fireworks or when left home alone - Reduces or eliminates separation anxiety ## Images ![Central Life Sciences 6-Pack Comfort Zone Refill with Dog Appeasing Pheromone, 288ml - Image 1](https://images-na.ssl-images-amazon.com/images/I/61sWxGn1f9L.jpg) ## Customer Reviews ### ⭐⭐⭐⭐⭐ Calms Louie down *by L***I on May 15, 2014* We have a miniature dachsund who is very high strung, even at 4 years old. Our vet recommended anxiety medication because he would get so worked up when we left. Our trainer recommended we try this instead. It works great, we also bought the spray and spray a little in his kennel and have this plugged in where he sleeps, He is alot calmer when we leave and sleeps alot better at night. I would recommend this to anyone who has issued with a dog that has a hard time relaxing and calming down. ### ⭐⭐⭐⭐⭐ What a relief! *by A***L on January 26, 2012* We adopted a lovable but neurotic dog 9 years ago. She would chew up and destroy everything she could when left alone, busting out of her kennel to do so. I thought I'd never be able to leave my home safely again! I read extensively trying to find some help, picking up little tips here and there, discovering Comfort Zone in the pet store. Took it home, plugged it in, dog ran over, looked up at me quite puzzled, as if to say "What the heck?" then she laid down and went to sleep for several hours. It did help her calm down quite a bit. We used it fairly steadily for a year or 2, and now use it from time to time, when Daisy has to spend a lot of time home alone. It really works, comforting dogs because it smells like their nursing mommy dog. (To other dogs, humans smell nothing) We have our own proof of that. We had been using D.A.P. and going to obedience class. The weather turned cold, and we closed up our windows, making the pheromone more concentrated. At the next class, none of the younger dogs could stay in there position while we did our walk around the gym. All the puppies got up and wanted to follow our mommy-scented Daisy!I've recommended Comfort Zone over and over again, along with the most helpful book on dog behavior I've ever read. And I've read many. The Dog Listener, by Jan Fennell, is to dogs what the Horse Whisperer is to horses. If you dog jumps on you and you can't stop him, read this book. If your dog goes nuts when you go out, read this book. Basically, if you have any problem with your dog, read this book! The Dog Listener: Learn How to Communicate with Your Dog for Willing Cooperation ### ⭐⭐⭐⭐⭐ Excellent *by L***H on October 27, 2015* We rescued a basset hound with aggression and biting problems. We went thru two trainers with little success. The third one took a more calming, holistic approach including using the DAP product. We keep it near where Roscoe sleeps and have used it for several months. We are confident that this has been beneficial to calming Roscoe. --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.pt/products/16666788-central-life-sciences-6-pack-comfort-zone-refill-with-dog](https://www.desertcart.pt/products/16666788-central-life-sciences-6-pack-comfort-zone-refill-with-dog) --- *Product available on Desertcart Portugal* *Store origin: PT* *Last updated: 2026-04-24*