---
product_id: 184412720
title: "The Great Cholesterol Myth, Revised and Expanded: Why Lowering Your Cholesterol Won't Prevent Heart Disease--and the Statin-Free Plan that Will - National Bestseller"
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---

# The Great Cholesterol Myth, Revised and Expanded: Why Lowering Your Cholesterol Won't Prevent Heart Disease--and the Statin-Free Plan that Will - National Bestseller

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- **What is this?** The Great Cholesterol Myth, Revised and Expanded: Why Lowering Your Cholesterol Won't Prevent Heart Disease--and the Statin-Free Plan that Will - National Bestseller
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## Description

The best-selling book on heart disease, updated with the latest research and clinical findings on high-fat/ketogenic diets, sugar, genetics, and other factors. Heart disease is the #1 killer. However, traditional heart disease protocols—with their emphasis on lowering cholesterol—have it all wrong. Emerging science is showing that cholesterol levels are a poor predictor of heart disease and that standard prescriptions for lowering it, such as ineffective low-fat/high-carb diets and serious, side-effect-causing statin drugs, obscure the real causes of heart disease. Even doctors at leading institutions have been misled for years based on creative reporting of research results from pharmaceutical companies intent on supporting the $31-billion-a-year cholesterol-lowering drug industry. The Great Cholesterol Myth reveals the real culprits of heart disease , including: inflammation, fibrinogen, triglycerides, homocysteine, belly fat, triglyceride to HDL ratios, and high glycemic levels. Best-selling health authors Jonny Bowden, PhD, and Stephen Sinatra, MD, give readers a four-part strategy based on the latest studies and clinical findings for effectively preventing, managing, and reversing heart disease, focusing on diet, exercise, supplements, and stress and anger management. Myths vs. Facts Myth : High cholesterol is the cause of heart disease. Fact : Cholesterol is only a minor player in the cascade of inflammation which is a cause of heart disease. Myth : Saturated fat is dangerous. Fact : Saturated fats are not dangerous. The killer fats are the transfats from partially hydrogenated oils. ​ Myth : The higher the cholesterol, the shorter the lifespan. Fact : Higher cholesterol protects you from gastrointestinal disease, pulmonary disease, and hemorrhagic stroke. Myth : High cholesterol is a predictor of heart attack. Fact : There is no correlation between cholesterol and heart attacks. Myth : Lowering cholesterol with statin drugs will prolong your life. Fact : There is no data to show that statins have a significant impact on longevity. Myth : Statin drugs are safe. Fact : Statin drugs can be extremely toxic including causing death. Myth : Statin drugs are useful in men, women, and the elderly. Fact : Statin drugs do the best job in middle-aged men with coronary disease. Myth : Statin drugs are useful in middle-aged men with coronary artery disease because of its impact on cholesterol. Fact : Statin drugs reduce inflammation and improve blood viscosity (thinning blood). Statins are extremely helpful in men with low HDL and coronary artery disease.

Review: Dr. Sinatra was and still is a life saver - Years ago, as new young nurse, I remember working on the cardiology floor at in Manchester Memorial Hosptal in Connecticut. There, Dr Sinatra was beloved and deeply respected. The older nurses who were training me called him the "wonderkid doc", like "Here comes the wonderkid doc to make his rounds". I asked why they called him that. They replied, "Because almost all his patients get better!" And that, let me assure you, did not normally happen on the cardiology floor. He was the nicest guy, but more importantly, he was the cardiologist, despite his baby face, that you wanted your beloved grandpa with heart disease to be a patient of. Well, now it's decades later, and I no longer work in that field or even live in that region. Frankly, I'd long ago forgotten about hospital nursing and Dr. Sinatra. But researching my own seemingly alarming lab results, I stumbled onto this book. I wanted to make informed decisions about what my current doctor was reccomending (Statins), but had these vague memories from my work in Connecticut at that hospital that were giving me pause on the whole accepted notions regarding cholesterol and its role in heart disease. Seeing the name of Dr. Sinatra as the author obviously rang a bell, so I looked him up, and sure enough, he was that same smiling, warmhearted cardiologist from the 1990's, just not so baby faced anymore. Knowing that he was way beyond smart, caring and deeply respected way back there in my Connecticut hospital days, I bought this book without hesitation, and am so grateful for the education it provided. It has changed my understanding of cholesterol, heart disease and its causes, and enabled me to actually feel able to prevent heart disease. This will not be via statins or by worrying about eating too much grass fed beef or cheese, but by controlling sugar/"bad" carb intake, which leads to insulin resistance, which leads to pre-diabetes, which is what really leads to heart disease. These conditons create the environment that damages the sub-type of cholesterol that is an issue, to allow it to become deformed into a dangerous shape, and to insert itself where it shouldn't, in the walls of arteries. He argues very convincingly that the amount cholesterol is not the problem for most of us-it is found at the scene of the accident, but it is not the root cause of the accident . He has a way of explaining complicated scientific concepts in a way even kids can grasp, which is a rare gift. For those who feels he and his co-author ignored research or studies and are re-writing accepted medical facts, I strongly disagree. I did the work of looking up many of the studies cited in the bibliography and many more studies released since this book was published in pubmed. His explanation of how modern medicine got here by believing the cherry picked data from the JUPITER ('Justification for use of statins preventatively, or something like that name....') study, was quite a revelation to me, since only data from a few countries out of the 18 countries collected from was actually used to promote the authors preconceived conclusion. Countries with traditionally low "bad" carb intakes had data that completely contradicted the 'high cholesterol causes heart disease so you need statins to lower it' conclusions, so the majority of the countries studied had their data simply omitted. I found this book reliable, thorough, comprehensible, and despite being a few years old, in agreement with more current published studies. The majority of people will read on their favorite news site, "studies say such and such causes such and such ....." , and they will believe the interpretation of the author without looking up and reading the study for themselves, finding out if it had 50,000 or only five participants, etc. They will not be aware if the author(s) of the study has a bias, or if the study itself was free of financial conflicts of interests, or if it was sponsored by a pharmecutical corporation. These authors have looked at the original studies, who did the, the data they show regarding heart disease, cholesterol, diebetes, etc, and have come to starkly different conclusions than many others. I believe they have done a huge service for many of us searching for accurate information free from financially motivated bias. This book will help many of us to make educated decisions and to take care of ourselves and our loved ones as best we can and prevent heart disease and its leading causes. TLDR: 1. Your triglycerides to HDL ratio matters the most. The higher it is, the higher your risk. It should be a low ratio, 1:1 is best. If your HDL is 80 and your triglyceides are 80, Dr. Sinatra believes you can throw away the book because your risk is so low. 2. Don't eat much sugar or (bad) carbs because they are literally giving us heart disease. 3. Statins are antiinflammatory and may benefit men under age 69 years old who have already had a coronary event or are at a very high risk. But they also do a lot of other things that might not be so good, especially for women and for everyone age 70 or older.So maybe read the book, get a CT score scan and some more detailed bloodwork, talk to your doc about the findings, and make more thoroughly educated decisions.
Review: A MUST READ! For anyone with high triglycerides & insulin resistance. - The info provided in this extremely eye opening book is backed up by case study citations. My LDL cholesterol & triglycerides have been high since my early 30’s, despite being a vegetarian, a highly competitive athlete, in good physical shape, and avoiding animal fats as was recommended by the AMA during the 80’s and beyond. I was never able to comprehend how in the world my cholesterol was so elevated despite my “ healthy vegetarian” lifestyle. I just “assumed” it was my genetics. Hmmmm. We all have been told for decades that animal fats are bad for us & will cause high cholesterol and heart disease. Enter margarine, highly processed seed oils, and man made “Frankenfats”. I had squarely fallen into this mindset, and have lived my life avoiding full fat foods and always sought out low fat or no fat everything. So now in my 60’s my insulin resistance is impaired, I have a mild case of NAFL, and my triglycerides are high. Hmmmmm. At one point a Dr. put me on a statin and it messed me up so badly, I took myself off it. Chronic leg pain and severe brain fog. It was horrible. Not to mention it didn’t really decrease my cholesterol. A friend of mine gave me a copy of this book to borrow, and after reading the first 10 pages I bought my own copy. The info and studies throughout this book have convinced me that in my case, my no fat or low fat way of life was NOT a healthy way for me to live. And for me, my health was definitely paying the price for it since I avoided healthy fats and ate more carbs. for more than 3 decades. Argggh For the past 8 months we have eaten locally grown grass fed meats, I render my own local pork fat for lard, eat full fat cheese, free range organic eggs, forest raised pork/bacon, and organic butter. My triglycerides have dropped 103 points and my insulin resistance is starting to drop. We have cut out all packaged foods. Eliminated all seed oils, and 95% of wheat and corn products. As well as dropped our carbohydrate intake to occasional sweet potatoes, quinoa, or rice. We eat a lot of walnuts, raw almonds, cashews, and pumpkin seeds. Eating a healthy nutrient dense fats and lowering carb intake switches your metabolism to burn the fat first and give you more energy. It has worked for me. We are sleeping better, feeling better, have more energy, no brain fog, and I have shed the 10 lbs. I have never been able to get rid of despite all of my cardio exercise. We feel a lot better eating this way and the bloodwork results are proving it for me. Not saying that this would work for everyone, as we all have very different circumstances. But, it is clearly working very well for us. Give the book a read and come to your own conclusions. It just might help you take control of your own health situations and help improve them. It certainly did for us!

## Technical Specifications

| Specification | Value |
|---------------|-------|
| Best Sellers Rank | #6,381 in Books ( See Top 100 in Books ) #3 in Heart Disease (Books) #3 in Cardiovascular Diseases (Books) #3 in Cardiology (Books) |
| Customer Reviews | 4.7 out of 5 stars 2,010 Reviews |

## Images

![The Great Cholesterol Myth, Revised and Expanded: Why Lowering Your Cholesterol Won't Prevent Heart Disease--and the Statin-Free Plan that Will - National Bestseller - Image 1](https://m.media-amazon.com/images/I/81xdg2PwDTL.jpg)

## Customer Reviews

### ⭐⭐⭐⭐⭐ Dr. Sinatra was and still is a life saver
*by A***A on July 31, 2024*

Years ago, as new young nurse, I remember working on the cardiology floor at in Manchester Memorial Hosptal in Connecticut. There, Dr Sinatra was beloved and deeply respected. The older nurses who were training me called him the "wonderkid doc", like "Here comes the wonderkid doc to make his rounds". I asked why they called him that. They replied, "Because almost all his patients get better!" And that, let me assure you, did not normally happen on the cardiology floor. He was the nicest guy, but more importantly, he was the cardiologist, despite his baby face, that you wanted your beloved grandpa with heart disease to be a patient of. Well, now it's decades later, and I no longer work in that field or even live in that region. Frankly, I'd long ago forgotten about hospital nursing and Dr. Sinatra. But researching my own seemingly alarming lab results, I stumbled onto this book. I wanted to make informed decisions about what my current doctor was reccomending (Statins), but had these vague memories from my work in Connecticut at that hospital that were giving me pause on the whole accepted notions regarding cholesterol and its role in heart disease. Seeing the name of Dr. Sinatra as the author obviously rang a bell, so I looked him up, and sure enough, he was that same smiling, warmhearted cardiologist from the 1990's, just not so baby faced anymore. Knowing that he was way beyond smart, caring and deeply respected way back there in my Connecticut hospital days, I bought this book without hesitation, and am so grateful for the education it provided. It has changed my understanding of cholesterol, heart disease and its causes, and enabled me to actually feel able to prevent heart disease. This will not be via statins or by worrying about eating too much grass fed beef or cheese, but by controlling sugar/"bad" carb intake, which leads to insulin resistance, which leads to pre-diabetes, which is what really leads to heart disease. These conditons create the environment that damages the sub-type of cholesterol that is an issue, to allow it to become deformed into a dangerous shape, and to insert itself where it shouldn't, in the walls of arteries. He argues very convincingly that the amount cholesterol is not the problem for most of us-it is found at the scene of the accident, but it is not the root cause of the accident . He has a way of explaining complicated scientific concepts in a way even kids can grasp, which is a rare gift. For those who feels he and his co-author ignored research or studies and are re-writing accepted medical facts, I strongly disagree. I did the work of looking up many of the studies cited in the bibliography and many more studies released since this book was published in pubmed. His explanation of how modern medicine got here by believing the cherry picked data from the JUPITER ('Justification for use of statins preventatively, or something like that name....') study, was quite a revelation to me, since only data from a few countries out of the 18 countries collected from was actually used to promote the authors preconceived conclusion. Countries with traditionally low "bad" carb intakes had data that completely contradicted the 'high cholesterol causes heart disease so you need statins to lower it' conclusions, so the majority of the countries studied had their data simply omitted. I found this book reliable, thorough, comprehensible, and despite being a few years old, in agreement with more current published studies. The majority of people will read on their favorite news site, "studies say such and such causes such and such ....." , and they will believe the interpretation of the author without looking up and reading the study for themselves, finding out if it had 50,000 or only five participants, etc. They will not be aware if the author(s) of the study has a bias, or if the study itself was free of financial conflicts of interests, or if it was sponsored by a pharmecutical corporation. These authors have looked at the original studies, who did the, the data they show regarding heart disease, cholesterol, diebetes, etc, and have come to starkly different conclusions than many others. I believe they have done a huge service for many of us searching for accurate information free from financially motivated bias. This book will help many of us to make educated decisions and to take care of ourselves and our loved ones as best we can and prevent heart disease and its leading causes. TLDR: 1. Your triglycerides to HDL ratio matters the most. The higher it is, the higher your risk. It should be a low ratio, 1:1 is best. If your HDL is 80 and your triglyceides are 80, Dr. Sinatra believes you can throw away the book because your risk is so low. 2. Don't eat much sugar or (bad) carbs because they are literally giving us heart disease. 3. Statins are antiinflammatory and may benefit men under age 69 years old who have already had a coronary event or are at a very high risk. But they also do a lot of other things that might not be so good, especially for women and for everyone age 70 or older.So maybe read the book, get a CT score scan and some more detailed bloodwork, talk to your doc about the findings, and make more thoroughly educated decisions.

### ⭐⭐⭐⭐⭐ A MUST READ! For anyone with high triglycerides & insulin resistance.
*by S***H on July 29, 2023*

The info provided in this extremely eye opening book is backed up by case study citations. My LDL cholesterol & triglycerides have been high since my early 30’s, despite being a vegetarian, a highly competitive athlete, in good physical shape, and avoiding animal fats as was recommended by the AMA during the 80’s and beyond. I was never able to comprehend how in the world my cholesterol was so elevated despite my “ healthy vegetarian” lifestyle. I just “assumed” it was my genetics. Hmmmm. We all have been told for decades that animal fats are bad for us & will cause high cholesterol and heart disease. Enter margarine, highly processed seed oils, and man made “Frankenfats”. I had squarely fallen into this mindset, and have lived my life avoiding full fat foods and always sought out low fat or no fat everything. So now in my 60’s my insulin resistance is impaired, I have a mild case of NAFL, and my triglycerides are high. Hmmmmm. At one point a Dr. put me on a statin and it messed me up so badly, I took myself off it. Chronic leg pain and severe brain fog. It was horrible. Not to mention it didn’t really decrease my cholesterol. A friend of mine gave me a copy of this book to borrow, and after reading the first 10 pages I bought my own copy. The info and studies throughout this book have convinced me that in my case, my no fat or low fat way of life was NOT a healthy way for me to live. And for me, my health was definitely paying the price for it since I avoided healthy fats and ate more carbs. for more than 3 decades. Argggh For the past 8 months we have eaten locally grown grass fed meats, I render my own local pork fat for lard, eat full fat cheese, free range organic eggs, forest raised pork/bacon, and organic butter. My triglycerides have dropped 103 points and my insulin resistance is starting to drop. We have cut out all packaged foods. Eliminated all seed oils, and 95% of wheat and corn products. As well as dropped our carbohydrate intake to occasional sweet potatoes, quinoa, or rice. We eat a lot of walnuts, raw almonds, cashews, and pumpkin seeds. Eating a healthy nutrient dense fats and lowering carb intake switches your metabolism to burn the fat first and give you more energy. It has worked for me. We are sleeping better, feeling better, have more energy, no brain fog, and I have shed the 10 lbs. I have never been able to get rid of despite all of my cardio exercise. We feel a lot better eating this way and the bloodwork results are proving it for me. Not saying that this would work for everyone, as we all have very different circumstances. But, it is clearly working very well for us. Give the book a read and come to your own conclusions. It just might help you take control of your own health situations and help improve them. It certainly did for us!

### ⭐⭐⭐⭐⭐ Must read!
*by V***G on April 28, 2026*

Very informative. Gave to my cardiology NP to read. Has helped me take less medication.

## Frequently Bought Together

- The Great Cholesterol Myth, Revised and Expanded: Why Lowering Your Cholesterol Won't Prevent Heart Disease--and the Statin-Free Plan that Will - National Bestseller
- The Truth About Statins: Risks and Alternatives to Cholesterol-Lowering Drugs
- The Great Cholesterol Con: The Truth About What Really Causes Heart Disease and How to Avoid It

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*Last updated: 2026-05-17*