--- product_id: 3048441 title: "Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats | with 1% Hydrocortisone, 1.25oz" price: "€ 59.17" currency: EUR in_stock: true reviews_count: 13 url: https://www.desertcart.pt/products/3048441-advanced-formula-otic-plus-enzymatic-ear-solution-for-dogs-cats store_origin: PT region: Portugal --- # Gentle, no pre-cleaning needed LP3 Enzyme System for biofilm breakdown 1% Hydrocortisone for itch relief Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats | with 1% Hydrocortisone, 1.25oz **Price:** € 59.17 **Availability:** ✅ In Stock ## Summary > 🐾 Clear ears, happy pets—because they deserve the best care! ## Quick Answers - **What is this?** Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats | with 1% Hydrocortisone, 1.25oz - **How much does it cost?** € 59.17 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.pt](https://www.desertcart.pt/products/3048441-advanced-formula-otic-plus-enzymatic-ear-solution-for-dogs-cats) ## Best For - Customers looking for quality international products ## Why This Product - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Soothes & Protects:** 1% Hydrocortisone calms itching and redness fast, restoring comfort to your pet. - • **Vet-Trusted Relief:** Clinically proven to ease recurrent ear issues caused by germs, fungi, and yeast. - • **Effortless Application:** No pre-cleaning required—clean, mess-free use even on sensitive, painful ears. - • **Biofilm-Busting Enzymes:** Advanced LP3 Enzyme System targets stubborn microorganisms for deep ear cleansing. - • **All-Age, All-Species Care:** Safe for dogs and cats of every age, making it the go-to solution for your furry family. ## Overview Zymox Advanced Formula Otic Plus is a vet-recommended enzymatic ear solution for dogs and cats that combines the LP3 Enzyme System with 1% Hydrocortisone to effectively break down biofilms, soothe itching, and relieve redness without the need for pre-cleaning. Safe for pets of all ages, it offers fast, gentle relief from stubborn ear infections caused by bacteria, fungi, and yeast, ensuring your furry companions stay comfortable and healthy. ## Description desertcart.com : Zymox Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats | with 1% Hydrocortisone, 1.25oz : Pet Ear Care Supplies : Pet Supplies Review: Fast Relief, Clean Application, No Strong Smell - My dog had been scratching one ear a lot, and it was getting hard to ignore. I wanted to try something at home first before going to the vet, so I gave this a shot. The bottle is simple and easy to handle, and the applicator tip helps keep things clean when applying it. The liquid itself is clear, slightly thick (not watery), and doesn’t really have a noticeable odor, which I liked because it didn’t bother my dog at all. After using it as directed, I noticed a difference pretty quickly. By the second use, he had already stopped scratching so much and seemed a lot more comfortable. That was honestly the biggest thing for me. What stood out is how clean the application feels (no mess), the texture of the product, and that it doesn’t have a strong scent. It also seems gentle enough, since my dog didn’t react negatively and stayed calm during use. One small thing is that you still have to apply it carefully, especially if your dog moves a lot. Seeing him relaxed again and not constantly scratching made a big difference. I’d definitely keep this on hand in case it happens again. Review: Best pet ear cleaning product on the market - I have been an desertcart customer for years and this may be the best product I have ever bought on desertcart. I have a cat that has had major ear problems for years. He's been to the vet on numerous locations who have treated him for infections as well as a deep cleaning of his ears and nothing has worked. I hate seeing my cat suffer like this so I decided to take a chance in this product. Well this miracle product works. I followed the directions exactly and used it for seven full days. I noticed an improvement after 3 days but after 7 days, the cat's ear problems are almost completely gone. Although he shakes his head from time to time, the itching is pretty much gone and his ears are much cleaner. I am now following this care with the Zymox ear cleaning pads from time to time. I highly recommend both of these products. Just follow the directions. Thank you Zymox! ## Features - Cat and dog ear cleaner, soothes recurrent ear issues, itching and redness, for pets of all ages - Relief from stubborn ear problem-causing microorganisms that form complex, irritating biofilms - Gentle formula helps relieve painful ear issues caused by resistant germs, fungi and yeast - Pet ear solution, no pre-cleaning of painful ears needed; safe, natural alternative to medication - LP3 Enzyme System to help clear ear exudate; 1% Hydrocortisone for itchy ears ## Technical Specifications | Specification | Value | |---------------|-------| | Customer Reviews | 4.7 out of 5 stars 14,857 Reviews | ## Images ![Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats | with 1% Hydrocortisone, 1.25oz - Image 1](https://m.media-amazon.com/images/I/512WnsXPqIL.jpg) ## Questions & Answers **Q: How is Zymox Plus different from Zymox (with the blue label)? both say 1.0 hydrocortisone.** A: My veterinarian said just to use the regular Zymox. It’s $10 cheaper and has the exact same ingredient. I looked it up myself. You can see the active ingredient in the inactive ingredient. Everything is the same. It’s kind of like the namebrand Excedrin. They they packaged their product in different ways. They have Excedrin for headaches Excedrin for migraine. Exactly the same product. A lot of companies do that apparently. Hope this helps **Q: how do you get all the wax off the inside of the ears where it flushes out from the ear drops** A: This is a bit thicker, kind of like the consistency of neosporin, so if your dogs ears are really wax-y right now, I would suggest doing a light cleaning before putting this in the ears. Once you put the zymox into the ear, rub your dogs ears kind of in a circular motion to help massage the solution down into the ear canal, and then just let it sit and do it's thing. Over time there will be less wax build up to clean out before applying the ointment. I now put it in my dogs ears about once every 10 to 15 days, just as maintenance and care, without needing any wax clean up before hand or afterwards. **Q: Is this supposed to be liquidy/thin like water (not thick)? What I received is a different consistency than the thicker regular zymox I'm used to.** A: I ordered and received a bottle this week and the solution is much thinner than the previous zymox plus otic-hc advanced formula bottles I've ordered. I haven't used it yet but just by shaking the bottle I can tell it is very liquidy compared to the bottle I have left over. I also compared the boxes and the box I received this week looks different as well. The font is different and the box has a different texture. I also read the paper inside and noticed a major typo on the one I just received. Instead of spelling "externa" they spelled "exernna" 🤦🏽‍♀️ The boxes have different lot numbers and the box that I have already opened has a later expiration date than the box I just received. I hope they didn't send me a knock off. This enzymatic solution usually works wonders on my Boxer and completely cures her ear infections when I use it as directed. I will update you on the effectiveness of the bottle I just received after I use it. **Q: is this the same as Mometamax 15g** A: No Different item Mometamax is stronger and is prescription medication. ## Customer Reviews ### ⭐⭐⭐⭐⭐ Fast Relief, Clean Application, No Strong Smell *by Y***I on April 24, 2026* My dog had been scratching one ear a lot, and it was getting hard to ignore. I wanted to try something at home first before going to the vet, so I gave this a shot. The bottle is simple and easy to handle, and the applicator tip helps keep things clean when applying it. The liquid itself is clear, slightly thick (not watery), and doesn’t really have a noticeable odor, which I liked because it didn’t bother my dog at all. After using it as directed, I noticed a difference pretty quickly. By the second use, he had already stopped scratching so much and seemed a lot more comfortable. That was honestly the biggest thing for me. What stood out is how clean the application feels (no mess), the texture of the product, and that it doesn’t have a strong scent. It also seems gentle enough, since my dog didn’t react negatively and stayed calm during use. One small thing is that you still have to apply it carefully, especially if your dog moves a lot. Seeing him relaxed again and not constantly scratching made a big difference. I’d definitely keep this on hand in case it happens again. ### ⭐⭐⭐⭐⭐ Best pet ear cleaning product on the market *by C***N on June 20, 2026* I have been an Amazon customer for years and this may be the best product I have ever bought on Amazon. I have a cat that has had major ear problems for years. He's been to the vet on numerous locations who have treated him for infections as well as a deep cleaning of his ears and nothing has worked. I hate seeing my cat suffer like this so I decided to take a chance in this product. Well this miracle product works. I followed the directions exactly and used it for seven full days. I noticed an improvement after 3 days but after 7 days, the cat's ear problems are almost completely gone. Although he shakes his head from time to time, the itching is pretty much gone and his ears are much cleaner. I am now following this care with the Zymox ear cleaning pads from time to time. I highly recommend both of these products. Just follow the directions. Thank you Zymox! ### ⭐⭐⭐⭐⭐ One happy dog mom. This stuff is amazing!! 🙌🏻 *by S***2 on June 23, 2026* This stuff works!!!! My beagle has ear issues with itching bad and the head shakes. I had her taken in to the vet and it was cleaned out with meds added and I left with $100 or more vet bill. My poor beagle had issues again months later so I looked on Amazon and found an ear flush that is amazing, but the issue wasn’t fully going away. I then found this product and gave it a try. No more vet visits this stuff cleared up her ear problems. It went from inflammation and dirty looking to a clear ear that is so clean and no issues. My sweet girl is so happy now. I highly recommend this product if your dog has itching, inflammation and the head shaking due to their ear bother them. I can’t believe how quickly and well this cleared my dog’s ear. It’s a heavier gel product too so it stays put. There’s also so much product to use. This will be a good thing to keep on hand instead of a vet visit for ear issues. ## Frequently Bought Together - Zymox Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats with 1% Hydrocortisone, 1.25oz - Zymox Advanced Enzymatic Ear Wipes for Dogs and Cats - for Dirty, Waxy, Smelly Ears - Premium Strength Ear Cleaner Wipes - Non-Irritating - Hypoallergenic - 100 ct - Zymox Ear Cleanser Solution for Dogs and Cats, 4oz --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.pt/products/3048441-advanced-formula-otic-plus-enzymatic-ear-solution-for-dogs-cats](https://www.desertcart.pt/products/3048441-advanced-formula-otic-plus-enzymatic-ear-solution-for-dogs-cats) --- *Product available on Desertcart Portugal* *Store origin: PT* *Last updated: 2026-07-13*