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💪 Stay dry, confident, and unstoppable—overnight protection that works as hard as you do!
Depend Night Defense Adult Diapers for Women (Medium, 60 count) provide up to 12 hours of maximum absorbency with a DryShield core that absorbs 30x its weight and locks in moisture as gel. Featuring OdorBlock technology for up to zero odors and crafted from soft, cotton-like fabric, these disposable incontinence underwear offer underwear-like comfort and a secure fit for waist sizes 31–37 inches. Ideal for overnight bladder leak protection, they combine advanced performance with discreet comfort to empower active, professional women to sleep confidently and wake refreshed.
















| ASIN | B0BLG84F6Q |
| Age Range (Description) | Adult |
| Age Range Description | Adult |
| Best Sellers Rank | #246 in Health & Household ( See Top 100 in Health & Household ) #5 in Incontinence Protective Briefs & Underwear |
| Brand | Depend |
| Brand Name | Depend |
| Color | Blush |
| Customer Reviews | 4.5 out of 5 stars 10,985 Reviews |
| Effective Absorbency Hours | 12 |
| Global Trade Identification Number | 10036000551645 |
| Incontinence Protector Size | Medium |
| Incontinence Protector Type | Adult Incontinence Underwear |
| Item Dimensions | 12 x 18.13 x 9.81 inches |
| Item Length | 12 inches |
| Item Weight | 8.8 pounds |
| Lining Description | Other |
| Manufacturer | Kimberly-Clark Corp. |
| Manufacturer Part Number | 10036000551645 |
| Material | Polypropylene |
| Material Type | Polypropylene |
| Material Type Free | Alcohol Free, Paraben Free |
| Model Number | 10036000551645 |
| Number of Items | 4 |
| Package Type Name | Box |
| Pattern | Solid |
| Recommended Uses For Product | Adult Incontinence, Urine Protection |
| Reusability | Disposable |
| Size | Medium |
| Target Audience | Unisex-Adults, Women |
| Unit Count | 60 Count |
| Water Resistance Level | Not Water Resistant |
| Weight Range | 54-81 kg |
L**A
These really work!
I bought these with a lot of hesitancy but I have many fractured and collapsed vertebrae in my spine and lost 5 inches in height causing a lot of nerve impingement. And unfortunately, much to my horror, bowel and bladder incontinence.. I finally broke down after cleaning up too many accidents, the Depends Night Defense. Please do measure yourself as directed and go by their size guide. I ended up with an XL,which I feared wouldn’t be big enough but they fit perfectly. I have some trouble getting them on because I can’t bend over much and a long time chronic illness has taken most of my muscle strength so even raising my leg,to put my foot through the leg opening, is challenging! I have a lot of gastrointestinal problems and a lot of bloating so I can’t tolerate tight clothes or waistbands. But I have no problem with the Depends. They not only fit but they’re comfortable. The waistband is very soft and stretchy and I just fold it over a bit. They fit perfectly and I hardly notice wearing them but I no longer have that terrible fear of incontinence and damaging clothes and furniture. This may be too much info but last night as usual, I had to pee really badly and ,as usual, couldn’t get off the couch (where I sleep) in time so I quit trying to fight it. Then being so sleepy and having difficulty getting off the couch (no strength)mi just flopped back down and went back to sleep! In the morning, the diaper was loaded so to speak, but everything else was dry! I was very pleased. Those nighttime trips to the commode or bathroom are a nightmare for me which is humbling to admit. They Åre leakproof for sure! And comfortable. Just buy the right size according to the measurements given. Yes, they’re expensive but I got a huge box that will last a long time I hope. At any rate, they are worth the cost in preventing accidents and peace of mind.
D**N
Extremely happy with these adult diapers!
I order these Depend Night Defense Adult Diapers regularly for my elderly mother, and they work great for her. She needs reliable overnight protection, and these have been a real help. They stay secure, keep her dry through the night, and don’t leak even when she shifts around in bed. The fit is comfortable and not bulky, so she can move and sleep without feeling restricted. I’ve tried other brands, but these consistently perform better for nighttime use. Easy to put on, soft against the skin, and give both of us peace of mind. Highly recommend if you’re looking for dependable overnight incontinence protection.
A**A
Good for Grandma
I purchased the Depend Night Defense Overnight Underwear for my 96-year-old grandmother, and they’ve truly been a game changer for her comfort and health. We use them every night and also on days when she’s not feeling well enough to get around easily. The fit is secure but gentle, with soft material that doesn’t irritate her skin. Most importantly, they keep her clean, dry, and protected through the night, which has greatly reduced the risk of UTIs, something we struggled with before switching to these. The overnight absorbency is excellent. Even after hours of wear, there’s no leaking, no odor, and she still feels fresh in the morning. The blush color is also a nice touch, it feels a bit more dignified than plain white. We’ve tried other brands, but these stand out for their combination of comfort, absorbency, and skin health. For caregivers, knowing your loved one is protected and comfortable brings incredible peace of mind. Highly recommend for anyone caring for an elderly family member or someone recovering from childbirth who needs reliable overnight protection.
P**L
Error on previous review
I started buying these diapers because the regular Depends were not absorbent enough but now these Depends Night Defense are not absorbent either when I purchase the box of 56 07-08-2026 I gave a negative review on Depends Night Defense in error. The negative review should have been on another urinary incontinence product.
L**.
Depend Night Defense Diapers. LJohnston
I wear a LG but lately they seem to be looser around the legs and sometimes there is a small leakage. They are very good for protection in daytime as well as at night. Best ones I’ve found so far.
A**S
Get them
Works great
M**I
Quieter and softer equals smaller size
Same great product. Overnights are expensive but true to size and even generous. Quality is great. HOWEVER THE SAME SIZE IN 7 drop pkg. HAS SHRUNK IN SIZE. They have updated material to "SOFT AND QUIET". To compensate the cost of upgrading they sacrificed material and made this same size smaller . They turned it into a hipster. This now reaches just below the navel and runs low on backside. Now I have to go up a size and this means I have to pay more for larger size pkg. . Depends is squeezing us into spending more money to justify materials needed to promote "QUIETER AND SOFTER MATERIAL " go somewhere else drop this mfg and buy ALWAYS BRAND
A**R
New style seams come apart
I just started using the new softer quieter ones and the seams come apart. I've always loved these but it is really an issue when you feel the seams tear and you need to figure out what to do. If I'm not at home it's not always convenient and having to go commando with bladder issues is stressful. Other than this major issue these are really comfortable. Hope this issue gets fixed. Maybe it was just a fluke with the batch I got
A**G
Funcionales
Cumplen du objetivo y son cómodos, solo que el precio varía de un mes a otro y se puede encontrar mas barato en tiendas de autoservicio y farmacias.
J**N
Great fit!!
Great fit
R**L
la compra fue en total 60 unidades y solamente llego 15 exijo que se me envie los 3 paquetes
Lo ocupo para una pesona adulta mayor con discapacidad la cual cuido hace 15 años me es muy util el ariculo pero nuestra economia nos en boyante tenemos 72 años de edad
T**M
DEPEND NIGHT DEFENSE OVERNITE UW MEDIUM FOR WOMEN 15CT - 4 COUNT CASE
This is the best in the market and I tried every single brand. Excellent price! At shoppers Drugmart regular price is a lot more. 2nd best is Tena just as good, but much thicker, so not as discreet if wearing it out of the house. ~~~~~~~~ DEPEND NIGHT DEFENSE OVERNITE UW MEDIUM FOR WOMEN 15CT - 4 COUNT CASE
B**A
Great product
Great product and not available in Small size in Australia. 5 day delivery is excellent. Will be ordering on a regular basis.
Trustpilot
3 days ago
1 month ago