







🛡️ Unlock your body's natural shield with every capsule!
Kirkman Biofilm Defense Disruptor is a scientifically crafted enzyme supplement designed to dissolve protective biofilms that shield harmful microorganisms. Featuring a unique blend including lipase and glucoamylase, it supports immune health and microbiome balance while being hypoallergenic and gentle enough for daily use by adults and children over 4. With 60 capsules per bottle, it’s a trusted ally for those seeking advanced digestive and immune support without common allergens or harsh ingredients.













| ASIN | B07SRDFZM2 |
| Best Sellers Rank | #58,288 in Health & Household ( See Top 100 in Health & Household ) #254 in Multi-Enzyme Nutritional Supplements |
| Customer Reviews | 4.4 4.4 out of 5 stars (833) |
| Date First Available | August 3, 2012 |
| Is Discontinued By Manufacturer | No |
| Item model number | KKM51892 |
| Manufacturer | Kirkman |
| Product Dimensions | 2.12 x 2.12 x 3.8 inches; 1.76 ounces |
T**E
I'm The Best Reviewer of ALL Time
This is my husband's account but I'm writing to tell you that this is GOLD in a bottle. I was peeing blood. I took the D-Mannose, drank LOTS of water, took probiotics and there was relief and the bloody pee stopped for a while. I only felt slight relief when I downed a half a bottle of powdered D Mannose for my UTI vs. the teaspoon you are supposed to take of that bottle. As soon as I forgot my dosage of D Mannose oh it was a razor blade feeling out of this world each time I peed. I was up all night in pain like probably when a man discovers a gold digger has him for 18 years. I was up, disturbed by this pain and was unable to sleep so I did a google search and found a blog about this Biofilm stuff. Truth is, I fell asleep and woke up in more pain and begged my husband to find this biofilm stuff at 1-2 am and then I passed out in pain and fell back asleep again. I was desperate. I did not want to pay the 40 bucks but I was in so much pain I didn't care. I didn't want to go 53 million in debt. I'm so glad I did, my relief was INSTANT the next time I peed. I think this might be killing other things as well. I started taking Solaray Yeast Cleanse pills because when you get a bladder infection well, I didn't want anymore pain anywhere else (if you know what I mean) so I just started taking them as a precaution. Normally when I take 6 of these pills on my first day I get terrible systemic yeast die off headaches. Not while taking the Biofilm, honey. Nada. I have noticed a slight runny nose but that is it. Overall, I just FEEL better. This is coming from someone who has a drugstore in the closet, of supplements. I've bought and used so many different ones for this and that over the years. Biofilm is a for sure staple in my house after this. I never understood the concept or even heard of it. Nobody is getting sick around here anymore. Ain't nobody got time fo dat! Amazing product and I'm probably the biggest skeptic of all time, kinda the same way Kanye is the greatest rapper of all time in his brain. If you feel sick when you take this it probably is the die off of whatever isn't supposed to be in your body so you can heal. Remember, you always feel worse before you get better. I had a number of supplements I was cramming down my throat for relief and none of them did anything for the two weeks I suffered. Also, lemon water gave great relief as well. I did cherry juice in my juicer, cranberry... no relief. Who knows, maybe it helped but I didn't notice. Neither did the razor blades coming out of my pee hole. The D Mannose was good but I did get the bloody pee back again from my forgetting to take it... as soon as I took this, literally within the next two times I peed; no more blood and no more razor blades coming out. I'm just so thankful it worked for me right away, the way it did. If this is GOLD in a bottle, call me a gold digger because I'm sure my husband won't mind to go ahead and get down again. Thank you!!! I thought I was going to die before I took this. Thank you ten million times over.
K**J
Revisited
I have tried this twice now and both times got a violent reaction. I need some relief from constant UTI's that antibiotics can't cure. The reviews were so great so I really wanted it to work. Both times I tried, empty stomach. Two months in between attempts. Second time, within 3 hours I was nauseous, 4 hours I started vomiting. For the next two hours I vomited off and on, ended up with dry heaves, very painful. I know it probably is effective but evidently some of us can't take it. My loss. I revisited this product because of being desperate to get help. The UTI's persisted and I could no longer take the antibiotics. I went on the BioDefense but could not take it on an empty stomach. I had to put a little something in there before taking the pill. It made me able to tolerate it, I'm not sure how it affected the ability of it to work but the outcome was good. I took it in the morning. In the evening, with food, I took Oregano. I finished a whole bottle. The results are fantastic. I have not had a UTI in 7 months, before this I was getting them every couple of months. I also discovered another plus. I have suffered from h.Pylori and not been able to get rid of it even after multiple times with antibiotics. BioDefense helped me but I was just tested positive again. I think it is because the BioDefense peels away layers of the film and the h.Pylori repopulates. I haven't figured how to work this out yet but I think after the 2 weeks on the antibiotics I will go on BioDefense again and then try the Oregano again. I get very sick, nauseous all day long, with the h.Pylori so I am going to keep on until I can get it under control.
C**L
Effective
Never dealt with candida until more recently when I got oral thrush. It lingered and created a horrible biofilm coating on my tongue so I turned to biofilm disruptors so that medications would be effective. I alternate between kirkman and klaire labs for my disruptors as they contain different enzymes. Both work well but I think kirkman works exceptionally well. If youre dealing with biofilms these should absolutely be taken on an empty stomach away from other pills to maximize the benefits. I take four a day all at once. For me, a brief period of nausea will follow (only sometimes) about 45 min after taking these as the enzymes and lack of food contribute to it. I started getting noticeable results within a few days. Yes theyre expensive, but they work.
J**N
Use Cautiously
I'm not a practitioner but I would strongly urge caution when using this product (or a similar one like Interfase Plus). Although it can break down biofilm, it can also clear your gut of mucus, which serves as a protective barrier against pathogens, toxins, acids, enzymes, etc. I was advised by my dietitian to take 1 capsule 2 times per day for 30 days. I did experience die-off symptoms within the first week, which was a clear indication that the product was working. However, throughout the treatment, I saw an abundance of mucus in my stool, and after 30 days, my GI tract burned and I experienced headaches nearly all the time. My guess is that the Biofilm Defense eliminated much of the mucus in my gut, which lead to some irritation, inflammation, and perhaps even damage to my intestinal lining. Now, our bodies produce about 10 liters of mucus per day and it increases production in response to injury, so I think I'll be okay. But I think it's clear this product should be used cautiously. According to Dr. Paul Anderson, most biofilm disruptors will do what they can (given the maturity of the pathogenic biofilms present - check him out to learn more) within the first few weeks of use. Again, my condition imroved only in the first week. Had I known then what I know now, I probably would have stopped there or shortly after.
D**R
I wish it was more affordable
Love the product, but it’s just too expensive so I’m going to be looking for something that is comparable and less expensive
Trustpilot
3 days ago
1 month ago